Description:
Multiplate®ASPItest isareagentkit usedformonitoringofAspirin®andothercycloxygenaseinhibitorsinroutineplateletaggregationstudiesfortheevaluationofnormalplateletfunctionontheMultiplate®Analyzer. TheASPItestreagentisalyophilizedpreparationofarachidonicacid(AA),stockconcentration15mM.
Pleasenotethecatalog#forMultiplate®ASPItesthaschangedto08115826001.Youmayhavepreviouslyorderedthisundercatalog#sMP0210 or06675816190.
KitComposition:
Reagents,StorageandStABIlity
- 08115826001:Multiplate®ASPItestreagent, Kit,3x1.0ml.150tests.Stableuntiltheexpirationdateprintedonthe viallabelwhenstoredat2-8°C.
Alsoavailable
- 06675662190: Multiplate®ASPItestAliquotVials,Bag, 100 colorcodedmicrotesttubesforaliquotation.
Nolongeravailable
- MP0191:Multiplate®ASPItestreagent,Kit,1x1.0ml.50tests
- MP0110:Multiplate®ASPItestreagent,Bag, 1x1.0ml,5colorcodedmicrotesttubesfor aliquotation.50tests.
MeasurementPrinciple:
IntheASPItest,plateletsareactivatedbyarachidonicacid,whichisconvertedbytheplateletcyclooxygenaseenzyme(COX-1)tothepotentplateletagoNISTthromboxaneA2.ArachidonicacidaloneisnotaplateletagonistandisthephysiologicalsubstrateoftheplateletCOX-1.Therefore, plateletactivationintheASPItestallowsaverysensitiveandspecificdetectionofAspirin®action.
