Description:
ChromogenixAntithrombin 10IUisforthedeterminationofHeparininplasma.Antithrombininconjunctionwithheparinelikesubstancesisapotentinhibitorofthrombin,factorXa,factorXlaandfactorlXa. AntithrombinispreparedfromhumanplasmaandpurifiedbyaffinitychromatographywithanHeparineSepharosegelaccordingtotheprotocolofMiller-Anderssonetal.(Thromb.Res.5,439-452,1974).
Forlaboratoryuseonly.
Composition:
Lyophilizedpowderpreparedfromhumanplasmaafteraffinitychromatographyonheparin-Sepharosegel.ContainshumanalbuminasastABIlizer.
- LyophilizedhumanAntithrombin10lU±1
- Albumin12mg
- SodiumChloride9mg
Thelyophilizedpowderisstableat2-8°Cuntiltheexpirydateprintedonthelabel.ThereconstitutedAntithrombinisstablefor1monthat2-8°Cor6monthsat-20°CwhenusedforthedeterminationofHeparin,accordingtothetestconditionsofChromogenixCoatest®Heparin.
SpecificActivity: Above6IU/mgAntithrombin.
Note:Thispreparationisnotastandard.
EnzymeActivityDetermination:
Chromogenixantithrombin canbeused foranti-FXachromogenicassayswhereadditionofexogenousantithrombinisdesired.
TheactivityofFXacanbemeasuredusingthefollowingchromogenicsubstrates:
- Chromogenix®S-2222™,25mgvial,catalog#S820316(82031639)
- Chromogenix®S-2765™,25mgvial,catalog#S821413(82141339)
