Description:
Technoclot®PTOwren (manual)isathromboplastinreagentmodifiedaccordingtoOwrenforthequantitativedeterminationofProthrombinTime(PT)inhumancitratedplasmaandcapillaryblood.ThereagentisenrichedwithbovineplasmafromwhichtheprothrombincomplexfactorsII,VIIandXhavebeenremoved.ThebovineplasmaremainsasourceoffibrinogenandfactorV,whichthereforecannotbedetectedbythetest.
Technoclot®PTOwrenreplaces Thrombotest®andNormotest®.
Composition:
Thereagentislyophilizedandcontainsrabbitbrainthromboplastinandadsorbedbovineplasma.Theadsorbedplasmais addedasasourceoffactorVandfibrinogen.Technoclot®PTOwrenmanualisacombinedthromboplastinwhich alreadycontainsCaCl2.
Materialsrequired (notsuppliedwiththekit)
- Pipettes
Capillaries25µl,2x100pcs, Catalog# 9801025 - Distilledwater
- ControlPlasma*
CoagulationControlN,5x1ml,Catalog# 5020040
CoagulationControlAK,5x1ml, Catalog#5011050
CoagulationControlA,5x1ml, Catalog#5021055
Technoclot®PTOwrenCapillaryControlSet, Catalog#5005102 - CalibrationPlasma
AK-Calibrant,4x1ml, Catalog#5010004
CoagulationReference,5x1ml, Catalog#5220110
Technoclot®PTOwrenCapillaryCalibrationSet, Catalog#5005100
*oranyotherpackagesizesorTechnoclot®reagent
Summary:
ThisreagentissensitivetoabnormallevelsofthecoagulationfactorsII,VIIandX.Itisusedforthecontrolofbloodcoagulationdisordersoftheextrinsicsystemaswellasthemonitoringoforalanticoagulanttherapy(i.e.warfarin).Technoclot®PTOwrenmanualisespeciallydesignedtobeusedwithmanualmethods(i.e.tilting)andsemiautomatedcoagulometers.