
Description:
TheTechnothrombin®MPkitallowstodirectlyrelatethecirculatinglevelsofmicroparticlestothemicroparticleinducedthrombotictendency.
Measurementofmicroparticleswashamperedbylaboriousmethodstoisolateandcharacterizemicroparticlesorassayswhichdetermineonlyafractionofthrombogenicmicroparticles.TheTechnothrombin®MPkitallowsdirectdeterminationofthelevelsofcirculatingthrombogenicmicroparticles.Itincludesamicroparticlestandardaswellasamicroparticlehighandlowcontrolplasmasandallreagentsformeasurementofthrombingeneration.
Circulatingmicroparticles,between1.0and0.1μminsizearederivedfromapoptoticoractivatedcells,containphospholipids,proteinsandotherconstituentsfromtheirparentcellsandarethrombogenic.Microparticlesarethoughttobeapivotalriskfactorforthrombosisinthrombophilicsubjects.